In South Korea, Dong-A Pharmaceutical's Melatoning Cream, endorsed by actress Jeon Ji-hyun, is gaining attention for its efficacy in improving melasma and hyperpigmentation. Classified as an over-the-counter drug, it is sought after by consumers for its ability to gradually lighten excessively deposited melanin pigments in the skin.
The primary active ingredient in Melatoning Cream is 2% hydroquinone, which inhibits the tyrosinase enzyme responsible for melanin production, thereby reducing new pigment formation and fading existing discoloration. It is approved for use on various hyperpigmentation issues such as melasma, freckles, and age spots, and can also help with brown marks left after acne. The pharmacy price is approximately 22,000 KRW, though it may vary by pharmacy, and no prescription is required. With the lowest concentration among similar hydroquinone products like Melanosacream (4%) and Melably Cream (4%), it is often recommended for first-time users.
Bloggers emphasize the importance of sun protection when using Melatoning Cream, suggesting starting with a small amount only in the evening and gradually increasing frequency. They also advise performing a patch test due to potential skin irritation and applying a thin layer only to the hyperpigmented areas. Reviews indicate that applying it with a cotton swab or clean finger after basic skincare, once the skin is sufficiently dry, yields effective results.
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